| 122 |
Case Study/Series
|
Acetylated Regenerated Cellulose in the Treatment of chronic diabetic pressure ulcerations of the lower extremity First Author: Graham Frazier Authors: C. Graham Frazier, DPM Robert VanCourt, DPM, FACFAS Craig Broussard Ph.D, RN, CNS Purpose: To assess the efficacy of Acetylated Regenerated Cellulose (ARC) as a treatment option for Chronic Diabetic Ulcerations of the lower extremity. Methods: Prospective Case review of 10 subjects, 5 male and 5 female, age range 34 - 82 with Diabetes Mellitus (Type I or II), peripheral neuropathy, and lower extremity pressure ulcerations unresponsive to former treatment regimens for greater than 3 months. Exclusion criteria included infection such as cellulitis or osteomyelitis. Each subject was monitored weekly for 6 weeks. Daily dressing changes and offloading was prescribed along with debridement, as determined by Attending Physician Co-Author. Results: Subjects 1-4 (3 Female:1 Male) all wound dimensions increased(LxWxD) After review of Charts, all showed noncompliance in off-loading regimen. Subjects 5-10 (4 Male: 2 Female) - 8 Ulcerations ranging in dimensions (LxWxD) from 2.7 x 1.0 x 0.1 to 0.4 x 0.3 x 0.1. 4 showed complete epithelialization at the end of the 6 weeks. The 4 remaining ulcerations showed average decreases of 59% Length and 44% Width Conclusions: ARC appears to warrant further investigation as a treatment option for chronic diabetic ulcerations. When used in conjunction with adequate off-loading and patient compliance, the results of this small review appear promising. |
|