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Clinical Research
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An evaluation of hyperoxygenated fatty acid (HOFA) and its effects on the microcirculatory and barrier properties of the skin First Author: Fred Muniz Authors: David Brett HOFA is a technology based on the introduction or saturation of peroxides into fatty acid esters via the presence of ultraviolet light and controlled temperatures. This technology has been adopted as a method of preventing pressure ulcers and treating circulatory insufficiencies. It is felt that this therapy is effective due to the release of free oxygen thus promoting microcirculation at the site of application. The purpose of this study was to investigate the effects of HOFA on skin physiology such as local microcirculation, barrier properties & moisturization levels. Microcirculation was evaluated via Laser Doppler, Transepidermal Water Loss (TEWL) was evaluated via Servo Med EP2 Evaporimeter and Moisturization Value was evaluated via Nova DPM 9003. The results indicated a microcirculation increase of 28% upon application of HOFA. A reduction in the TEWL and an increased Moisturization Value were also observed. The data show a physical response to the application of HOFA to the skin. This investigation opens opportunities to further study the benefit of this technology/therapy as a potential pressure ulcer prevention therapy as well as a therapy to improve the barrier properties of the skin. |
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