2005 Symposium on Advanced Wound Care | |
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Laboratory Research
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In vitro properties of a new absorbent nanocrystalline silver dressing Rachael Benson, BSc(Hons), Cbiol MIBiol, Smith & Nephew Research Centre, York, UK; Lynne Armstrong, PGDip, BSc(Hons), Smith & Nephew Medical Limited, Hull UK A new absorbent antimicrobial barrier dressing has recently been developed for the management of exuding wounds, particularly suited to those which may be critically colonized or infected. The product consists of nanocrystalline silver coated onto a polyurethane wound contact layer, which is laminated to a highly absorbent foam with a water-proof backing layer. The objective of the in vitro testing was to evaluate and assess the product performance by testing the physical and antimicrobial characteristics. Test methods were developed to assess cushioning and fluid handling ability. Absorption and retention of wound exudate, with and without compression, was investigated over a number of days using simulated wound model apparatus. The antimicrobial performance was assessed against major wound pathogens such as Staphylococcus aureus and Pseudomonas aeruginosa in log reduction and zone of inhibition tests, demonstrating the ability to provide a barrier to bacteria, sustaining the effect over a number of days. The physical bacterial barrier action was assessed using a bacterial penetration test against Serratia marcescens. The results obtained demonstrate that this product has excellent sustained physical and highly effective antimicrobial properties, confirming that the product is well suited for its intended purpose and use. |
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